Published new results of studies of vaccine COVID-19
Preliminary totals of the research work vaccine COVID-19 in mice American organizations Moderna show that it does not increase the risk over severity of disease and that one dose can provide protection from COVID-19, the study, published
Preliminary totals of the research work vaccine COVID-19 in mice American organizations Moderna show that it does not increase the risk over severity of disease and that one dose can provide protection from COVID-19, the study, published on the last working day of the week on the resource bioRxiv, publishing scientific materials.
Previous studies of vaccines against viruses similar to SARS-CoV-2, showed that a vaccine against this type of virus have the ability to have the effect of causing grievous over the course of the disease when the vaccinated person is Then exposed to the pathogen, most people with weak immune systems. It is believed that this risk is a major obstacle that must be addressed before the vaccines can be safely tested on thousands of healthy people.
in the study, scientists introduced different numbers of the vaccine six-week mice, including dose considered not strong enough to induce a protective immune response. Then the researchers subjected mice exposed to the virus.
As the attention of scientists, Preliminary Data showed that the Vaccine is "potent immunogenic substance" neutralizing activity " can be achieved using one dose ". In addition, it is noted that "subprojective dose did not lead to enhanced immunopathology" after exposure to the virus in mice, that is, did not cause more than severe acute disease.
Further testing has shown that the Vaccine triggers a strong response neutralizing antibodies. This is something that ought to block the virus, so it does not hit the cells. The vaccine also protects the lungs from infection by coronavirus, with no signs of toxic effects.
information on mice, published by the National Institute of Allergy and infectious diseases of the United States and Moderna, while there are no guarantee that similar results will be obtained in human studies.
Moderna said Thursday that it plans in July to begin the final stage, where they will participate 30 thousand people.
in early March, the who announced the outbreak of the coronavirus pandemic. Everything in the world to have caught them over 7, 4 million people, more than 418 thousand lost their lives.
Relevant Data on the situation of COVID-19 in Russia and worldwide can be found on the portal stopmanager. Of the Russian Federation.
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