The 31-year-old star - who worked as a model and a stripper before embarking on a movie career - insists he doesn`t make career decisions to try and detract away from his looks and be taken seriously as an actor but looks for what makes a good story.
He said: "I won a genetic lottery, my parents are very good-looking people and so... But no, don`t make decisions on how people see you, just do f***ing good stories and characters.
"Don`t do them because you think they`re smart or because they counteract some other things you`ve played.
"If I tried to do something for my career and it didn`t work out, that would feel more empty and more like I made a mistake."
Channing admitted he feels like the "luckiest guy on the planet" because he loves his work so much.
He added to Total Film magazine: "I never felt like a model. Someone just saw me on the street.
"Then I got into acting and now I am so obsessed with acting it`s ridiculous. At the moment I just read, watch movies and create - that`s all I really wanna do. I feel like the luckiest guy on the planet."
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