The President of the United States believes that cooperation in the nuclear programme will open up opportunities for trade, investment and partnership in science among States. But in case of refusal of Iran expects global isolation. In its own statement, which was issued on the occasion of Nowruz - Persian New year, President Barack Obama announced that Iran should take advantage of the best opportunity for the normalization of relations with the United States. To achieve the desired result, the country needs to sign the agreement on its own nuclear program. With all this, according to the American favorite, in case of failure of power from the cooperation of Iran is waiting for reliable isolation from much of the world". The President of the United States stressed that the signing of the nuclear agreement will have a positive impact on the relations of States. "If you look from another angle, if the Iranian favorites can agree on a wise arrangement, this may lead to a new way - a way of increasing opportunities for the Iranian people. More trade relations with the world. More foreign investment and jobs, even for young Iranians. Many foreign investments and jobs, even for young Iranians. More cultural exchanges and opportunities for Iranian students to travel to another state. More partnerships in areas such as science, technology and innovation," Obama said. American favorite in their own treatment expressed optimism about the future of the Treaty. "For decades our powers were separated by mutual distrust and fear. I believe that at this point we have a historic opportunity peaceful method to solve this problem, an opportunity which we must not miss", " Obama said in a message to Iranian leaders. According to his statement, to date, Washington has been removed a number of restrictions in mitigating the Tehran on its nuclear program. "Now, our diplomats and our researchers are negotiating hoping to find a comprehensive solution that will destroy all the difficulties on the nuclear program of the Republic," said Barack Obama.